Book review:Systems Metabolic Engineering

Book Review: Recent Advances in Yeast Metabolic Engineering

Metabolic engineering.

Metabolic engineering is the science that combines systematic analysis of metabolic and other pathways with molecular biological techniques to improve cellular properties by designing and implementing rational genetic modifications. As such, metabolic engineering deals with the measurement of metabolic fluxes and elucidation of their control as determinants of metabolic function and cell physio...

Metabolic engineering

MetaCyc database http://metacyc.org/ MetaCyc is a database of metabolic pathways containing more than 1400 pathways from more than 1800 organisms. KEGG pathway database http://www.genome.jp/kegg/pathway.html The KEGG pathway database consists of a collection of manually-curated metabolic maps with connections to metabolite, enzyme and organismal data. KEGG also contains tools for reconstructing...

Free Download Patterns Based Engineering Book

Genetic-Metabolic Coupling for Targeted Metabolic Engineering.

Production of chemicals in microbes often employs potent biosynthetic enzymes, which can interact with the microbial native metabolism to affect cell fitness and product yield. However, production optimization largely relies on data collected from wild-type strains in the absence of metabolic perturbations, thus limiting their relevance to specific conditions. Here, we address this issue by cou...